GPX4 and COVID-19: In COVID-19 patients, altered iron metabolism, depletion of glutathione (GSH) (Kumar et al., 2022), inactivation of GPX4 (Muhammad et al., 2021), and up regulation of lipid peroxidation biomarkers strongly propose ferroptosis as a plausible mechanism for COVID-19 multi-organ affection, including neuropsychiatric sequelae (Yang and Lai, 2020).