TP53 and neoplasm: KEGG analysis showed that the DEGs between tumor tissues and peritumor tissues of HCC patients from the TCGA-LIHC dataset were enriched in several ferroptosis-related pathways, such as p53 signaling pathway, fatty acid metabolism, fatty acid degradation, arachidonic acid metabolism, and alanine, aspartate, and glutamate metabolism (Figure 1C).