Data from the TCGA LIHC cohort also confirmed that KLF7 expression was positively correlated with HMGB1 and RELA expression in HCC samples, and HCC patients highly co-expressing HMGB1/KLF7 or RELA/KLF7 had significantly poorer OS, especially in Asian subpopulations (Figure S7C-D). The gene discussed is RELA; the disease is hepatocellular carcinoma.