In TCGA LIHC samples, positive correlations were observed between KLF7 and TLR4 or PTK2 expression, and HCC patients with high levels of KLF7/TLR4 or KLF7/PTK2 co-expression exhibited an obviously poorer OS than patients with low levels (Figure S7A -B). Here, TLR4 is linked to hepatocellular carcinoma.