Acting as a scaffold, an aberrantly overexpressed lncRNA, KB-1980E6.3, interacts with the KH1-2 domain of IGF2BP1 to constitute a KB-1980E6.3/IGF2BP1/c-Myc signaling axis, which promotes the stability of c-Myc and maintains the stemness of breast cancer stem cells 28. The gene discussed is MYC; the disease is breast carcinoma.