Remarkably, IGF2BP2 governs glutamine uptake and metabolism by upregulating MYC, glutamic-pyruvic transaminase 2 (GPT2), and solute carrier family 1 member 5 (SLC1A5) in AML, which indicates that IGF2BPs could regulate amino acid metabolism in cancers 26. This evidence concerns the gene SLC1A5 and acute myeloid leukemia.