SLC16A1 and neoplasm: The implications for this SLC transporter axis in the TME are clear: Originating from aerobic or anaerobic glycolysis, lactic acid produced by tumor cells has an established role in polarizing TAMs to an M2‐like anti‐inflammatory, pro‐reparatory state and promoting tumor growth284; modulation of the SLC2a1/SLC16A1 axis provides a potential mechanism for apoptotic tumor cells to perform a similar, pro‐oncogenic role (Figure 4).