The frequencies of most of the genotypes and allelic variants did not differ significantly between the two groups, with the exception of a lower frequency of the VDR rs731236 (A/G) and GC rs4588 (G/T) variants, and a higher frequency of GC rs7041 (C/C) and GC rs4588 (G/G) variants in migraine patients, that disappeared after correction for multiple comparisons (Table 2). This evidence concerns the gene VDR and migraine disorder.