VDR rs222857045, 46 and VDR rs797523245 have been associated with the risk for Parkinson's disease, at least in the Asian population,46VDR rs731236 with the risk for Alzheimer's disease,45, 46 at least in Caucasians,47 and VDR rs1544410 and VDR rs7975232, respectively, with increased and decreased risk for mild cognitive impairment.47 This evidence concerns the gene VDR and Alzheimer disease.