SYVN1 and gastric cancer: To name a few: in the development of gastric cancer, the expression of circ_0061137 was aberrant and significantly reduced in GC tissues and cells, and overexpression of circ_0061137 could inhibit cell proliferation, migration and invasion while also inducing apoptosis, therefore, the inhibitory role of circ_0061137 in tumor development could be used as a potential biomarker for GC [13], circ_0071127 was reduced in expression in breast cancer and could further regulate HRD1 expression by sponging miR-513a-3p [14].