AKT3 and familial pancreatic carcinoma: For instance, in pancreatic cancer progression, circ_0086375 could function as a sponge for miR-486-5p and could regulate the process of pancreatic cancer progression through miR-486-5p [18], circ-AKT3 could act as a sponge for miR-296-3p to further regulate the development of renal cell carcinoma [17].