PAX6 and familial hyperaldosteronism: A later review showed that isolated FH could also be associated with PAX6 missense mutations in PD: c.227 C > G, and c.382 C > T.1 Matsushita I et al. also reported c.1095T > G mutation in a patient with FH and normal anterior segments and c.58 C > T mutation in patients with FH and posterior polar cataract [9].