Our results suggest that the ACE inhibition capacity of peptide Asp-Leu-Ser-Ser-Ala-Pro is important than the antioxidant activity of peptide Asp-Ser-Val-Ser-Ala-Ser-Pro in rats with induced hypertension using L-NAME, indicating that peptide 1 Asp-Leu-Ser-Ser-Ala-Pro derived from green basil leaves has a potential peptide to minimize complications or injuries from hypertension induced by L-NAME. This evidence concerns the gene ACE and Hypertension.