Compared to 4T1-lung, lungs of BALB/c mice bearing non-metastatic 67NR or 4T07 tumor showed higher values of the Cxcl1-to-S100a8 ratio, and the values suggested the likelihood of developing metastases was in the order of 4T1-lung > 4T07-lung > 67NR-lung, consistent with the activity of antitumor immunity in these MNs (Fig. 6d). This evidence concerns the gene CXCL1 and neoplasm.