GABARAPL2 and Nematoda infectious disease: However, unlike selective receptors such as NBR1 that mediate selective autophagy and promote the aggregation and subsequent targeting of ubiquitylated protein cargoes to ATG8-positive autophagosomes under stresses21, JAM1 is degraded by autophagy and jams mutants show increased formation of autophagosomes and higher resistance after nematode infection.