ADORA2A and neoplasm: We found that Adora2a was highly expressed by tumor-infiltrating myeloid population when compared with the spleen (online supplemental figure 5B,C) and this expression was significantly higher in the IOT-resistant model in terms of MFI (mean fluorescence intensity 10,000 vs 6700, p<0.0001) and % of Adora2a+ myeloid cells (15% vs 11%, p=0.009).