NT5E and neoplasm: Of these, 52 genes were selected for the signature (figure 7C), that according to our RNAseq data set were clearly associated with the pathway areas dependent on adenosine (hypoxia response, immunity, tumor stroma), were associated positively or negatively with PDAC prognosis, and were significantly co-expressed with CD73 and/or Adora2a in the PDAC genome data sets (TCGA or Bailey).