While the OncoPrism-HNSCC and PD-L1 predictions were concordant for most samples (73/100), for samples where the tests disagreed, PD-L1 IHC had more false positives (12) and false negatives (7) than OncoPrism-HNSCC (6 and 2, respectively; Table S4). Here, CD274 is linked to head and neck squamous cell carcinoma.