From the viability and migration results, we can conclude that five out of the eight candidate genes (IL1α, IL1β, IL8, CXCL2, and CXCL3) play important roles in increasing cancer cell survival and metastasis after being co‐cultured with macrophages, while the other three candidate genes (CCL20, C3, and CXCL1) did not show these effects. This evidence concerns the gene C3 and cancer.