IL1B and familial pancreatic carcinoma: reported that treating macrophages with recombinant proteins of IL1α, IL8, chemokine (C‐C motif) ligand 2 (CCL2), and urokinase‐type plasminogen activator (uPA) or pancreatic cancer cells overexpressing these proteins increased macrophage invasion.[59] In our study, we found that in addition to IL1α and IL8, IL1β could also increase macrophage infiltration.