OCs attach to the bone matrix after emerging from the monocyte/macrophage haematopoietic spectrum, destroying hydroxyapatite and collagen in bone tissue by secreting degrading enzymes such as V‐ATPases and cathepsin K.28, 29Previous research has shown that TDH has anti‐inflammatory and anti‐tumour properties.30 This evidence concerns the gene CTSK and neoplasm.