TBP and Huntington disease: Toxicity in flies with Q63 expression specifically in adult glia suggests a cell nonautonomous role of polyQ-expanded TBP that warrants further examination; cell nonautonomous effects for polyQ disease proteins have been described before in SCA7, HD, and SBMA (Todi et al. 2007a; Lieberman et al. 2019; Johnson et al. 2022b).