In the patients with SCA, we found a significant correlation between right lobe (RL) and LL stiffness and serum levels of Tg (RL [r = −0.439] and LL [r = −0.484]; P = 0.021) and fT3 (RL [r = −0.463] and LL [r = −0.386]; P = 0.012). This evidence concerns the gene TG and autosomal dominant cerebellar ataxia.