To explore the reason of the infertility of BPA-treated Gga1−/− male mice, we performed a histological analysis of the caudal epididymis by H&E staining and found fewer spermatozoa in the epididymal lumen of BPA-treated Gga1−/− mice than that of BPA-treated Gga1+/+ mice (Fig. 3A). The gene discussed is GGA1; the disease is Infertility.