YAP1 and cholesteryl ester measurement: Subsequently, this caused changes in the ECM mechanical properties and activation of transcriptional coactivator Yorkie (Yki) orthologs, Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (WWTR1, also known as TAZ), and β-catenin signaling pathways, leading to differentiation of regenerating CE to corneal squamous cell metaplasia [97].