Dedicator of cytokinesis 3 (DOCK3) is a regulator of muscle atrophy.[19] Genetic deletion of Dock3 in mice results in muscle atrophy and DOCK3‐deficient myoblasts are defective for myogenic differentiation.[19b] Individuals with loss‐of‐function DOCK3 variants develop ataxia and developmental delay and have low muscle tone from birth.[20] DOCK3 rs77031559 G is associated with muscle fiber size and strength in elite athletes.[21] These findings highlight the essential role of DOCK3 in the regulation of muscle growth and atrophy. This evidence concerns the gene DOCK3 and Global developmental delay.