Elevated protein levels of Fbxo32/atrogin1 and ubiquitin, two downstream signaling components of FOXO3, were shown in septic WT pigs, but not in septic ZBED6−/− pigs (Figure 4F), corroborating the resistance to sepsis‐induced muscle catabolism upon ZBED6 deficiency. This evidence concerns the gene FOXO3 and Sepsis.