Furthermore, ZBED6 has been implicated in the development of various diseases, such as colorectal cancer,[16] colitis,[17] and diabetes.[14, 18] The role of ZBED6 in the regulation of these pathologies prompted us to consider whether ZBED6 plays a significant role in sepsis‐induced muscle atrophy, and if so, how does it regulate this pathological process? Here, ZBED6 is linked to Sepsis.