Moreover, we found several “writers” and “readers” of m6A modification were up-regulated in PCOS group, including YTH N6-methyladenosine RNA binding protein 3 (Ythdf3) (Foldchange = 1.35, P < 0.05), heterogeneous nuclear ribonucleoprotein A2/B1 (Hnrnpa2b1) (Foldchange = 1.615713434, P < 0.05). The gene discussed is YTHDF3; the disease is polycystic ovary syndrome.