The results showed that the “CHANDRAN Metastasis DN” gene signature (genes downregulated in metastatic vs nonmetastatic prostate carcinoma) was the most enriched gene set across all gene sets depleted in PCa tumors with GATA2 gain/amplification in comparison with those GATA2 diploid tumors (Fig. 1l). The gene discussed is GATA2; the disease is prostate carcinoma.