GATA2 and neoplasm: Having established that GATA2 amplification is positively correlated with its elevated expression in PCa patient tumors and the expression levels of GATA2 are markedly upregulated over tumor progression to advanced stage and metastasis, displaying profound associations with poor clinical outcomes in PCa, we next sought to elucidate the mechanism underlying aberrant transcription control of GATA2 overexpression.