To further investigate the role of GATA2 upregulation in PCa, we performed siRNA or shRNA-mediated knockdown of GATA2 in diverse PCa cell lines, including LNCaP, LNCaP-1F5 (1F5), V16A and 22Rv1 (Fig. S3a, b). The gene discussed is GATA2; the disease is posterior cortical atrophy.