Based on our findings as described above, GATA2 exerted prognostic value in predicting PCa patient survival (Fig. 1g, h, o-q) and our previous study showing that RFX6 possesses clinical impact on PCa progression [40], we hence asked whether RFX6 together with GATA2 synergistically perform better in clinical PCa prognosis. Here, GATA2 is linked to posterior cortical atrophy.