LRRK2 and Parkinson disease: While miR-146a, miR-335-3p, and miR-335-5p supposed to have anti-inflammatory properties, were downregulated in idiopathic PD and LRRK2-PD patients as compared to control cohorts, pro-inflammatory miR-155 was upregulated in LRRK2 but not in idiopathic PD patients [287].