In samples from ET patients with JAK2 mutations, we focused on the analysis of 13 genes (ARG1, CAST, CD177, CLEC5A, DAPP1, EPS15, IGHM, IL18RAP, OLFM4, OLR1, RIOK3, SELP, and THBS1). This evidence concerns the gene CAST and essential thrombocythemia.