We observe positive colocalization [posterior probability (PP) > 80%] for 5 of 18 proteins with the same traits (ADGRE2 and total cholesterol [TC]; ANGPTL7 and BMI, waist-hip ratio; ITGB7 and TC; NOMO1 and LDL, TC; SEMA3F and BMI, alcohol use), supporting the two-sample MR results. The gene discussed is ADGRE2; the disease is alcohol drinking.