Serum Zn concentrations can be affected by various factors, including dietary intake; the status of Zn-binding proteins such as albumin, transferrin, and α-2-macroglobulin, diabetes mellitus, gastrointestinal disorders leading to malabsorption, heavy alcohol use, medications and various medical conditions that result in Zn depletion, and foods high in phytate content.70 The gene discussed is ALB; the disease is digestive system disorder.