文献检索:于2022年3月使用PubMed进行文献检索,检索表达式:(“Bruton's tyrosine kinase inhibitor” OR “BTK inhibitor” OR “BTKi” OR “ibrutinib” OR “acalabrutinib” OR “zanubrutinib” OR “orelabrutinib” OR “pirtobrutinib” OR “Tirabrutinib”)AND(“hypertension” OR“atrial fibrillation” OR “AF” OR “sudden cardiac death” OR “SCD” OR “ventricular arrhythmia” OR “VA” OR “cardiovascular diseases” OR “CVDs” OR “heart failure” OR “HF” OR “coronary atherosclerotic cardiopathy”),限定为英文出版物。. This evidence concerns the gene BTK and atrial fibrillation.