Paxillin, as a scaffold protein, is known to associate with β1-integrin in squamous cell carcinoma (Crowe & Ohannessian, 2004) and in Schwann cells (Chen et al, 2000) with its phosphorylation mediated by the c-Met receptor (Laukaitis et al, 2001). This evidence concerns the gene PXN and squamous cell carcinoma.