In neonatal rat models of hypoxia‐ischemia it has been found that PBM attenuated cognitive impairment, reduced brain injury and neuron loss, as well as prevented oxidative damage, mitochondrial fragmentation and cytochrome c release (Tucker et al., 2018; Yang et al., 2019; Yang et al., 2021). The gene discussed is CYCS; the disease is Cognitive impairment.