Overall, patients with isolated MOG-IgA presented at least 1 of the following imaging features: (1) myelitis (short or longitudinally extensive); (2) periventricular lesion; (3) tumefactive deep white matter lesion; and (4) brainstem lesion, resembling NMOSD, atypical MS, and atypical demyelination phenotypes (Figure 2C and D and eFigure 4 in Supplement 1). The gene discussed is CD79A; the disease is myeloid sarcoma.