WT exosome-donor mice developed phospho-α-Syn pathology along the ipsilateral side of nigrostriatal axis and the ipsilateral cortical areas, with simultaneous accumulation of p62 and ubiquitin within the phospho-α-Syn bearing TH positive somata, mimicking LBs present in PD brains [36], [45]. Here, SQSTM1 is linked to Parkinson disease.