Compared with mice receiving FMT from non-PSCI patients, the stroke model mice receiving FMT from PSCI patients had a higher abundance of Enterobacteriaceae, lower fecal butyrate levels, and significantly reduced expression of tight junction proteins associated with the BBB, such as ZO-1, Occludin, and Claudin-4 [70]. Here, TJP1 is linked to stroke disorder.