Chen et al. found that Bifidobacterium longum CCFM681 could alleviate colitis by promoting the secretion of conjugated linoleic acid, protecting the intestinal mechanical barrier, modulating the gut microbiota, and inhibiting the TLR4/NF‐κB pathway and associated proinflammatory cytokines.33 The gene discussed is NFKB1; the disease is colitis.