In addition, we identified 20 hub genes CDK1, CDC20, CCNA2, BUB1B, BUB1, CCNB1, MAD2L1, AURKB, PLK1, CCNB2, NCAPG, KIF11, CDCA8, AURKA, KIF2C, NDC80, CDC6, CDC45, ASPM and DLGAP5 in the MEbrown module associated with psoriasis. This evidence concerns the gene BUB1 and psoriasis.