Watt and colleagues in a systematic review involving 14,362 patients undergoing elective procedures showed that interleukin-6 and CRP responses were associated with the magnitude of the operative injury and the invasiveness of the operative procedure.”4 Postoperative levels of CRP have shown a strong correlation with complications in patients with major abdominal surgery.30 The dual measurement of albumin and CRP in patients with advanced esophageal cancer may offer prognostic parameters in evaluating patients being considered for palliative surgery.31 This evidence concerns the gene CRP and esophageal cancer.