In the dataset HNSCC_GSE103322, CDKN2A (Figs. 6A and 6B), BIRC5 (Fig. 6C), and PLAU (Fig. 6D) were mainly expressed in HNSCC malignant cells, and their proportions in malignant cells were 76.4%, 50.5%, and 58.9%, respectively (Suppl. The gene discussed is PLAU; the disease is head and neck squamous cell carcinoma.