Specifically, the greatest positively correlated immunoinhibitors included B7 homolog 4 (B7-H4, or VTCN1, rho =0.235, P < 0.001), transforming growth factor- β receptor type I (TGFBR1, rho =0.112, P = 0.009), and the negatively associated immunoinhibitors were adenosine A2a receptor (A2AR, ADORA2A, rho =−0.387, P < 0.001) and CD160 (rho =0.339, P < 0.001) in ccRCC. This evidence concerns the gene ADORA2A and nonpapillary renal cell carcinoma.