Consistently, it demonstrated higher LDHA, lower LDHB and LDHD, and stable LDHC expression in 110 ccRCC than 84 normal kidney tissues (P < 0.001, P < 0.001, P < 0.001, P > 0.05, Fig. 2B, Fig. S1c). Here, LDHD is linked to nonpapillary renal cell carcinoma.