LDHB and nonpapillary renal cell carcinoma: Furthermore, multivariate Cox regression analysis identified that pathological stage (HR 3.918, 95% CI = 1.827−8.400, P < 0.001) and LDHB (HR 0.025, 95% CI = 0.003−0.186, P < 0.001) were recognized as independent prognostic indicators for OS in ccRCC patients.