IDH1 and central nervous system cancer: We compared the differences between the high-risk and low-risk groups on the training set and test set and the results revealed that the proportion of IDH1 mutation was significantly higher in the low-risk group than in the high-risk group, regardless of whether the patient was affected by glioma cerebri (GC) (Fig. 6A) or low-grade glioma (Fig. 6C).