NUCB1 and differentiation degree (X2 = 6.89, P < 0.05), clinical stage (X2 = 9.18, P < 0.05), and lymphatic metastases (X2 = 4.07, P < 0.05) existed statistically significant, but not with gender (X2 = 2.07, P > 0.10), age (X2 = 0.04, P > 0.50), tumor site (X2 = 2.11, P > 0.10) and invasion of serosa (X2 = 2.11, P > 0.10), distant metastases (X2 = 0.22, P > 0.50). The gene discussed is NUCB1; the disease is neoplasm.