Nain et al. (2021) determined downregulation of METTL7A expression in sufferers with COVID-19 patient. Wang et al. (2021a) confirmed that METTL7A promotes odontogenic differentiation of human dental pulp stem cells. In addition, abnormal expression of METTL7A has been detected in thyroid (Zhou et al., 2017), choriocarcinoma (Jun et al., 2020), gastric (Sexton et al., 2020), osteosarcoma (Jia et al., 2021), Lung adenocarcinoma (Guo, Ma & Zhou, 2019), breast (McKinnon & Mellor, 2017), and colorectal cancers (Lacalamita et al., 2021). The gene discussed is TMT1A; the disease is osteosarcoma.