Recently increasing studies have discovered the phenomenon that higher serum ferritin concentrations are also related with metabolic disorders of pregnancy such as gestational diabetes (GDM), serum dyslipidemia, insulin resistance (IR) calculated by indexes such as homeostasis model assessment-insulin resistance (HOMA-IR), homeostasis model assessment-insulin secretion (HOMA-IS), and homeostasis model assessment- β cell function (HOMA-β) (6) (7) (8) (9). The gene discussed is INS; the disease is Insulin resistance.