First of all, obesity or too much fat in the body will produce insulin resistance, stimulate the synthesis of triglycerides [13], increase the production of xanthine oxidoreductase in obesity [20], and stimulate the secretion of uric acid in the adipose tissue by regulating human metabolism and lead to the imbalance of uric acid metabolism and even develop into hyperuricemia. The gene discussed is XDH; the disease is obesity due to melanocortin 4 receptor deficiency.