TNF-α is another key proinflammatory cytokine that promotes immune cell migration towards the skin resulting in keratinocyte proliferation, which is one of the hallmark manifestations of psoriasis (Conrad and Gilliet, 2018; Ogawa et al., 2018; Ovcina-Kurtovic and Kasumagic-Halilovic, 2022). The gene discussed is TNF; the disease is psoriasis.