Additionally, serum S100A7 (psoriasin) and S100A12 (calgranulin-c) were found to be elevated in psoriasis patients, with the latter being regarded as the most promising S100 protein biomarker thus far in terms of correlating with severity of psoriasis (Wilsmann-Theis et al., 2016). This evidence concerns the gene S100A7 and psoriasis.