BCL2 and diffuse large B-cell lymphoma: Complete loss of FOXP1 results in the hindering of earlyB-cell development, whereas the increase of FOXP1 expression by theloss of miR-34a induces an increase in the production of mature B-cells.51 This interaction is critical in mucosa-associatedlymphoid tissue (MALT) diffuse large B-cell lymphoma (DLBCL) cells,in which it has been observed that inactivation of P53, low levelsof miR-34a, elevated levels of FOXP1, and Bcl-2 overexpression areassociated with unfavorable prognosis in the patients.52