Correlations between mutations in the adenoma group and cancer group were analyzed (Figure 3), focusing on the 10 overlapping mutated genes between the two groups: APC, ARID1A, FAT1, FBXW7, GNAQ, KRAS, LRP1B, MUC16, TP53, TTN, and ZFHX3. In the adenoma group, co-occurrences related to the 10 genes were found between the gene pairs GNAQ-PDGFRB, KRAS-SOX9, LRP1B-KMT2D, and LRP1B-TP53. The gene discussed is LRP1B; the disease is cancer.