Ladders used for gradual reintroduction of food allergens into a food allergic individual's diet are increasingly being used internationally.70 The formal milk-ladder can be used for reintroduction in non-IgE mediated food allergy (FPIAP, and food protein induced enteropathy—FPE) and might be considered in carefully selected cases of IgE-mediated CMA and CM-FPIES to evaluate for tolerance after a period of therapeutic elimination diet (Table 2).60 This evidence concerns the gene IGHE and Abnormal intestine morphology.