In a Dutch family study, it was found that of three individuals with a BP1–BP2 microduplication in a seven-member family, all exhibited autism symptoms (van der Zwaag et al., 2010), which highlights the need to study phenotypes related to enhanced dosages of the four genes located in this region−in particular Nipa1/2 and Cyfip1, which are highly expressed in the brain. This evidence concerns the gene CYFIP1 and autism.