Carbohydrate sulfotransferase 11 mRNA expression was increased by 3.1 times (N = 9, P < 0.001) and CHST15 expression was 2.1 times (N = 15, P < 0.001) higher in the vascular smooth muscle cells of COVID-19 patients that had severe lung manifestations (79). The gene discussed is CHST11; the disease is COVID-19.