When each monocyte subset from Pv and HD was compared, we observed that despite expressing a considerable number of genes in common, most of the genes analyzed are highly expressed only in the monocytes from Pv (Figure 3C, right panel), corroborating the hypothesis that Pv infection causes substantial changes in the expression of purinergic receptors by monocyte. The gene discussed is P2RX7; the disease is infection.