Overexpression of LAT1 is also closely related to the proliferation of cancer cells, such as lymphoma, esophageal cancer, lung cancer, and prostate cancer cells (156), owing to the critical role of SLC7A5 in activating mTORC1 signaling and metastasis in tumors (156, 170). The gene discussed is SLC7A5; the disease is Familial prostate cancer.